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KMID : 0360220080490081330
Journal of the Korean Ophthalmological Society
2008 Volume.49 No. 8 p.1330 ~ p.1334
Late-onset Migrated Inflammatory Granuloma After Collagen-Containing Filler Injection
Jo Young-Joon

Lee Sung-Bok
Lee Deok-Goo
Abstract
Purpose: To report a case of inflammatory granuloma in the right medial canthal area which occurred seven years after a cosmetic collagen-containing dermal filler injection in the forehead.

Case summary: A-47-year-old female, who had been treated with collagen-containing filler 7 years earlier, presented with a mass in the right medial canthal area discovered 20 days previously. There was mild tenderness and the mass was firm and not fixed. The patient reported that the size of the mass was slowly increasing. Orbital computed tomography and magnetic resonance imaging showed an approximate 1 cm-sized, poorly defined, enhancing nodular thickening without evidence of bony erosion. The mass was removed through a skin incision and unidentified foreign bodies were found around the mass. On histopathologic examination, it was diagnosed as inflammatory granuloma caused by foreign substances.

Conclusions: Collagen-containing fillers are widely used in cosmetic surgery for their lasting effect and few complications. However some complications such as inflammatory granuloma may occur at the injection site or other sites, even several years after operation. J Korean Ophthalmol Soc 49(8):1330-1334, 2008
KEYWORD
Collagen, Filler, Granuloma
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